Synthesize vs. Synthesise: What's the Difference?
By Janet White || Updated on November 13, 2023
"Synthesize" and "synthesise" are the same in meaning, referring to the process of combining parts to form a whole, differing only in regional spelling: "synthesize" is American English, while "synthesise" is British English.
Key Differences
"Synthesize" is the American English spelling used to describe the process of combining different elements to create something new. "Synthesise" is the British English variant of the same word, carrying the same meaning and usage.
Both "synthesize" and "synthesise" can be used in various contexts, such as chemistry, music, and intellectual discourse, to indicate the creation or formation of something by combining separate elements. The choice between the two spellings depends on the regional language preference.
In scientific contexts, such as in chemistry, "synthesize" (or "synthesise") refers to the process of creating compounds by chemical reactions. Both spellings are correct and interchangeable, depending on the regional English being used.
In literature or argumentation, to "synthesize" (or "synthesise") means to integrate ideas or data into a coherent whole. This usage is consistent in both American and British English, with only the spelling differing.
"Synthesize" and "synthesise" are perfect examples of how English language adapts to different cultural and regional variations, demonstrating the fluidity and adaptability of language.
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Comparison Chart
Spelling
American English
British English
Meaning
Combining elements to form a whole
Combining elements to form a whole
Usage
Same in various contexts
Same in various contexts
Pronunciation
Identical
Identical
Regional Preference
Used in the United States
Used in the United Kingdom and other Commonwealth countries
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Synthesize and Synthesise Definitions
Synthesize
In music, to produce sound electronically.
The artist used a synthesizer to synthesize unique sounds.
Synthesise
In electronic music, to generate sounds using a synthesizer.
She used her keyboard to synthesise a range of musical notes.
Synthesize
To integrate different ideas in writing or speech.
Her essay synthesizes theories from different fields.
Synthesise
In science, to create a substance through chemical reaction.
The chemist was able to synthesise a new medication.
Synthesize
In chemistry, to produce a compound by a chemical reaction.
The lab successfully synthesized a new form of plastic.
Synthesise
To combine various elements to create something new.
The author aimed to synthesise concepts from different philosophies.
Synthesize
To combine parts into a coherent whole.
The study aims to synthesize the findings from various experiments.
Synthesise
To amalgamate diverse ideas in an argument or discussion.
His thesis synthesises old and new theories.
Synthesize
To form by combining elements logically.
The theory synthesizes historical data with current trends.
Synthesise
To logically construct a theory or idea from various sources.
The researcher synthesised the data into a compelling argument.
Synthesize
To combine so as to form a new, complex product
"His works synthesize photography, painting and linguistic devices" (Paul Taylor).
Synthesise
Standard spelling of synthesize
Synthesize
To form or produce by chemical synthesis.
Synthesise
Combine so as to form a more complex, product;
His operas synthesize music and drama in perfect harmony
Synthesize
To produce (sound or music) by means of a synthesizer.
Synthesize
To form a synthesis.
Synthesize
(transitive) To combine two or more things to produce a new product.
Synthesize
To be combined producing a new, more complex product.
Synthesize
To produce a substance by chemical synthesis.
Synthesize
To be produced by chemical synthesis.
Synthesize
To combine by synthesis; to unite.
Synthesize
To produce by synthesis; as, to synthesize albumin.
Synthesize
Combine so as to form a more complex, product;
His operas synthesize music and drama in perfect harmony
Synthesize
Combine and form a synthesis
FAQs
Do synthesize and synthesise have different meanings in different contexts?
No, their meanings remain consistent across contexts, only the spelling changes.
Is the pronunciation of synthesize and synthesise different?
No, they are pronounced the same way.
Which spelling should I use in academic writing?
Use the spelling consistent with the variety of English you are writing in (American or British).
Are synthesize and synthesise the same?
Yes, they have the same meaning but different regional spellings.
Can I use synthesize in British English?
It's more common to use "synthesise" in British English.
Will British readers understand synthesize?
Yes, British readers will understand it as it's a common variance in spelling.
Is synthesize used in American scientific publications?
Yes, "synthesize" is the preferred spelling in American scientific literature.
Can synthesise be used in American English?
It can be used, but "synthesize" is the standard American spelling.
Are there any differences in usage between the two words?
No, their usage is identical; the difference is purely in spelling.
Is synthesize commonly used in American textbooks?
Yes, "synthesize" is commonly used in American educational materials.
Does the spelling change the word's meaning in any context?
No, the meaning of synthesize and synthesise remains the same regardless of the spelling.
Should I change synthesise to synthesize for an American audience?
Yes, adapting spelling to your audience's version of English is often recommended.
Can non-native speakers use either spelling?
Non-native speakers should use the spelling consistent with the variety of English they are learning or using.
Is synthesize used in official documents in the U.S.?
Yes, "synthesize" is the preferred spelling in official American documents.
Is it wrong to use synthesise in an American publication?
It's not wrong, but it's less standard than "synthesize" in American English.
Are there any variations in the definition of synthesize/synthesise?
No, the definitions are consistent; only the spelling differs based on regional use.
Is there a preferred spelling in international publications?
International publications often choose one version of English and stick to its spelling conventions.
Are there any synonyms for synthesize/synthesise?
Terms like "combine," "integrate," or "amalgamate" can be similar in meaning.
Can I use both spellings interchangeably in a document?
It's best to stick to one spelling for consistency within a single document.
Should I change my spelling of synthesize/synthesise based on my audience?
Yes, adapting your spelling to your audience's regional English is a good practice.
About Author
Written by
Janet WhiteJanet White has been an esteemed writer and blogger for Difference Wiki. Holding a Master's degree in Science and Medical Journalism from the prestigious Boston University, she has consistently demonstrated her expertise and passion for her field. When she's not immersed in her work, Janet relishes her time exercising, delving into a good book, and cherishing moments with friends and family.