Advantix vs. Frontline: What's the Difference?
Edited by Aimie Carlson || By Janet White || Published on October 3, 2024
Advantix is a flea and tick treatment that also repels mosquitoes, whereas Frontline is a treatment that kills fleas, ticks, and lice but doesn't repel mosquitoes.
Key Differences
Advantix and Frontline are both topical solutions used to protect dogs from fleas, ticks, and other parasites. Advantix, produced by Bayer, is distinguished by its ability to repel and kill ticks, fleas, and mosquitoes. It contains permethrin and imidacloprid, ingredients not safe for cats, making it exclusive for use in dogs. Frontline, on the other hand, is a widely used flea and tick preventive available for both dogs and cats. Its active ingredient, fipronil, works by disrupting the central nervous system of parasites.
One of the main differences between Advantix and Frontline is their action against mosquitoes. Advantix provides a repellant action that is beneficial in areas where mosquito-borne diseases like heartworm are prevalent. This makes Advantix a preferred choice for dog owners living in or traveling to regions where such risks are higher. Frontline's formulation is safe for use in cats, an advantage for multi-pet households that include both cats and dogs. This aspect is crucial considering the toxicity of permethrin (found in Advantix) to cats.
Both Advantix and Frontline are applied topically and provide a month's worth of protection. Choosing between them often depends on the specific needs of the pet and the preferences of the pet owner, considering factors such as the presence of mosquitoes in the environment and whether both dogs and cats are in the household.
Comparison Chart
Active Ingredients
Permethrin, Imidacloprid
Fipronil, (S)-methoprene (Frontline Plus)
Repels Mosquitoes
Yes
No
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Safe for Cats
No
Yes
Parasites Targeted
Fleas, ticks, mosquitoes, biting flies
Fleas, ticks, lice
Application
Topical
Topical
Advantix and Frontline Definitions
Advantix
Prevents ticks from attaching to dogs and transmitting diseases.
Advantix has kept our dog tick-free during our hikes in the woods.
Frontline
Kills parasites on contact without the need for them to bite.
Frontline ensures that fleas are killed as soon as they touch my pet.
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Advantix
A topical solution for dogs that repels and kills fleas, ticks, and mosquitoes.
After applying Advantix, the dog was no longer bothered by mosquitoes.
Frontline
Requires monthly application for optimal protection.
Every first of the month is Frontline day for our pets.
Advantix
Offers protection against biting flies and lice in addition to fleas and ticks.
With Advantix, even the biting flies avoid our dog at the beach.
Frontline
A topical flea and tick treatment effective for both dogs and cats.
We use Frontline for all our pets to keep them free of fleas and ticks.
Advantix
Not safe for use in cats due to its permethrin content.
Because we have cats, we can't use Advantix in our household.
Frontline
Does not repel mosquitoes but effectively controls flea and tick infestations.
Even though Frontline doesn't repel mosquitoes, it's our choice for flea and tick control.
Advantix
Needs to be applied once a month for continuous protection.
I mark my calendar every month to apply Advantix on my dog.
Frontline
Protects pets from lice in addition to fleas and ticks.
Since using Frontline, our cat has been lice-free.
Frontline
A front or boundary, especially one between opposed military forces.
Frontline
A position or situation of direct involvement in a conflict or struggle
Doctors on the front line of the campaign against cholera.
FAQs
How quickly does Advantix work?
Advantix starts killing fleas within 12 hours of application.
Is Advantix safe for puppies?
Yes, Advantix is safe for puppies over 7 weeks old.
Can Frontline be used on kittens?
Yes, Frontline is safe for kittens over 8 weeks of age.
How long does Frontline take to kill fleas?
Frontline kills most fleas within 24 hours of application.
How long after application can my pet swim or be bathed when using Frontline?
Frontline is water-resistant 24 hours after application.
Is Frontline effective against all stages of fleas?
Yes, Frontline Plus is effective against all stages of the flea life cycle.
How often should Advantix be applied?
Advantix should be applied once a month for continuous protection.
Can Frontline repel mosquitoes?
No, Frontline does not repel mosquitoes.
What should I do if my dog is allergic to Advantix?
Discontinue use and consult your veterinarian for alternative treatments.
Does bathing affect the efficacy of Advantix?
Advantix remains effective after bathing, though it's recommended to avoid bathing 48 hours before and after application.
Can Advantix be used on cats?
No, Advantix is toxic to cats and should not be used on them.
Can Frontline be used on pregnant pets?
Consult your veterinarian, but Frontline is generally considered safe for pregnant pets.
Is Frontline safe to use around other pets?
Yes, Frontline is safe to use around both dogs and cats.
How does Frontline Plus differ from Frontline?
Frontline Plus includes an additional ingredient, (S)-methoprene, to kill flea eggs and larvae.
What parasites does Frontline not protect against?
Frontline does not protect against mosquitoes and certain tick species.
Can I apply Advantix more frequently than once a month?
It's recommended to follow the monthly application schedule unless advised otherwise by a vet.
What happens if I accidentally apply Advantix to my cat?
If Advantix is applied to a cat, seek veterinary care immediately as it can be lethal.
Can I use Frontline year-round?
Yes, Frontline can and should be used year-round for continuous protection.
Are there any side effects of using Advantix?
Some pets may experience skin irritation or allergic reactions. Consult a vet if symptoms persist.
Does Advantix expire?
Yes, check the packaging for the expiration date to ensure its efficacy.
About Author
Written by
Janet WhiteJanet White has been an esteemed writer and blogger for Difference Wiki. Holding a Master's degree in Science and Medical Journalism from the prestigious Boston University, she has consistently demonstrated her expertise and passion for her field. When she's not immersed in her work, Janet relishes her time exercising, delving into a good book, and cherishing moments with friends and family.
Edited by
Aimie CarlsonAimie Carlson, holding a master's degree in English literature, is a fervent English language enthusiast. She lends her writing talents to Difference Wiki, a prominent website that specializes in comparisons, offering readers insightful analyses that both captivate and inform.
